A Factor Underlying Late-Phase Arrhythmogenicity After Cell Therapy to the Heart: Global Downregulation of Connexin43 in the Host Myocardium After Skeletal Myoblast Transplantation
نویسندگان
چکیده
منابع مشابه
A factor underlying late-phase arrhythmogenicity after cell therapy to the heart: global downregulation of connexin43 in the host myocardium after skeletal myoblast transplantation.
BACKGROUND Arrhythmia occurrence is a variable but serious concern of cell therapy for treating heart failure. Using a rat postinfarction chronic heart failure model, we compared skeletal myoblast (SMB) with bone marrow cell (BMC) injection to highlight donor cell-specific, late-phase arrhythmogenesis and the underlying factors. METHODS AND RESULTS SMBs or BMCs derived from male GFP-transgeni...
متن کاملGlobal Downregulation of Connexin43 in the Host Myocardium After Skeletal Myoblast Transplantation
Copyright © 2008 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/CIRCULATIONAHA.107.779629 2008;118;S138-S144 Circulation Suzuki Anabel Varela-Carver, Husein Salem, Kenta Yashiro, Magdi H. Yacoub and Ken Steven R. Coppen, Satsuki Fukushima, Yasunori Sh...
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ژورنال
عنوان ژورنال: Circulation
سال: 2008
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.107.779629